Adverse Cardiovascular Events with Nonsteroidal Anti-inflammatory Agents

Authors

  • Antonis S Manolis Evagelismos General Hospital, Athens

DOI:

https://doi.org/10.2015/hc.v10i2.716

Keywords:

non-steroidal anti-inflammatory drugs, osteoarthritis, rheumatoid arthritis, cardiovascular disease, hypertension, risk factors, gastrointestinal tract

Abstract

The extensive use of nonsteroidal anti-inflammatory drugs (NSAIDs), both nonselective and cyclooxygenase- 2–specific inhibitors, for the relief of acute and chronic musculoskeletal pain, in addition to gastrointestinal toxicity, confers serious cardiovascular toxicity that affects the overall risk/benefit ratio of this commonly employed therapy. A plethora of studies have provided convincing evidence for a high risk of adverse cardiovascular events associated with NSAIDs related to a number of risk factors, which are herein briefly reviewed and an algorithm is suggested for their safer use.

Author Biography

Antonis S Manolis, Evagelismos General Hospital, Athens

Specialty: Cardiology

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Published

2015-05-25

Issue

Vol. 10 No. 2 (2015)

Section

EDITORIAL

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