The Role of Levocarnitine in the Management of Valproic Acid Intoxication: A Case-Based Review

Authors

  • Fotis Panagopoulos
  • Sofia Dymenou
  • Vasilis Stamatopoulos
  • Ioanna Papaodyssea
  • Natalia G Vallianou

Abstract

The administration of L-carnitine to patients with VPA intoxication and CNS depression with normal ammonia concentrations has a rationale, on the grounds that it is a safe compound with no severe adverse effects reported. Herein, we present a case of valproate poisoning with normal ammonia levels and discuss about the therapeutic as well as the prophylactic potential of L-carnitine administration in such cases.

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Published

2023-05-10